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Gene expression analysis of M. tuberculosis in patients with and without HIV co-infection
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Gene expression analysis of M. tuberculosis in patients with and without HIV co-infection
Group 3: Anne Skov-Pedersen s184330, Dea F. Skipper, Helene B. L. Petersen s194699, Johanne B. Overgaard s194691 and Rebecca C. Grenov
Introduction
Co-infection with tuberculosis (TB) is the leading cause of death in HIV-infected individuals. However, diagnosis of TB, especially in the presence of an HIV co-infection, can be limiting due to the high inaccuracy associated with the use of conventional diagnostic methods. Here we report a gene signature that can identify a tuberculosis infection in patients co-infected with HIV as well as in the absence of HIV.